War and Peace is awesome. So is Crime and Punishment.
Also Shantaram is a cool book. There were plans to make it into a movie with Johnny Depp but that seems to be on hold.
I also like Angry White Pajamas - it's about an English guy who goes to Japan and trains in Aikido.
A few recent favourites:
One Hundred Years of Solitude - Gabriel Garcia Marquez
Small Gods - Terry Prachett
Guards! Guards! - Terry Prachett
A Song for Arbonne - Guy Gavriel Kay
All-time Favourites:
The Lord of the Rings (trilogy)
Interview with the Vampire - Anne Rice
Yeah, I'm mostly into the fantasy genre.